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Febuxostat prevents gout flares in recent clinical trial

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The Drug febuxostat reduced gout flares in a double-blind, placebo-controlled study of 314 adults with early gout. Febuxostat treatment also reduced synovitis — or inflammation of the joint lining detected by MRI scanning — over a 2-year period compared with placebo. Febuxostat treats high urate in the blood of patients with gout. “Current clinical practice guidelines do not recommend routine use of urate-lowering therapy for people after the first gout flare. This study indicates that even for people who have had only 1 or 2 prior gout flares, urate-lowering therapy to reduce serum urate below 6mg/dL may have benefit in reducing future flares,” said Dr. Nicola Dalbeth, lead author of the study.

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Prototype UT equipment can detect rheumatoid arthritis

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According to a first clinical study published in the scientific journal Photoacoustics, the University of Twente and various European partners have designed a device that shows the difference between healthy fingers and arthritic fingers. The University of Twente and Ziekenhuis Groep Twente researchers responsible for the development of the compact device believe that it may in time help doctors to objectively diagnose the degree of inflammation in joints.

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Running with prosthetic lower-limbs: Advantage or disadvantage?

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Researchers at Bournemouth University have been looking at the impact of lower-limb prosthetics on competitive running, specifically looking at whether athletes with prosthesis are at an unfair advantage when running against athletes without prosthetics.

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Prosthetic arm technology detects spinal nerve signals

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To control the prosthetic, the patient has to think like they are controlling a phantom arm and imagine some simple manoeuvres, such as pinching two fingers together. The sensor technology interprets the electrical signals sent from spinal motor neurons and uses them as commands. A motor neuron is a nerve cell that is located in the spinal cord. Its fibres, called axons, project outside the spinal cord to directly control muscles in the body. Robotic arm prosthetics currently on the market are controlled by the user twitching the remnant muscles in their shoulder or arm, which are often damaged. This technology is fairly basic in its functionality, only performing one or two grasping commands. This drawback means that globally around 40-50 per cent of users discard this type of robotic prosthetic.

View related article at Orthopedics.

Tiny bubbles help heal broken bones, in pigs

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Researchers have developed a much needed alternative to bone grafts that could help alleviate the long-term hospitalization, disability, and considerable costs to the health system associated with non-healing fractures.

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Bone marrow transplant

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Bone marrow transplantation (BMT) or hematopoietic stem cell transplantation (HSCT) is a medical procedure in the field of hematology and oncology that involves transplantation of hematopoietic stem cells (HSC). It is most often performed for people with diseases of the blood or bone marrow, or certain types of cancer.

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Making bones stronger

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They may seem rigid and set in their ways, but your bones are actually under constant construction and deconstruction. They give up their nutrient treasures (calcium) to the body and then rebuild in a constant give-and-take sort of rhythm. When that rhythm shifts with advancing age or the onset of osteoporosis, the rebuilding process decreases. Bones lose density and strength and become more prone to fracture. More than 10 million people in the United States live with osteoporosis and the resulting fractures demand more than $17 billion in related health care each year.

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