Clinical

Skeleton

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Skeleton acts as a supporting structure of an organism. The organisms with skeleton are known as vertebrates and without skeleton are known as invertebrates. There are different types of skeleton; they are exoskeleton, endoskeleton, cytoskeleton, hydro skeleton, pliant skeleton and rigid skeleton. Mostly at the age of 21, the bone masses of the skeleton reaches its maximum density. The primary function of skeleton is to support, movement, protection, production of blood cells, storage of minerals, and endocrine regulation.

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Rheumatoid arthritis

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Rheumatoid arthritis is systemic disease and one of the autoimmune diseases. It is an inflammatory disease in which the cartilage damages and creates pain. This auto immune disease can affect more than joints like other body parts like skin, eyes, lungs, heart, and blood vessels

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Inflammatory diseases

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Inflammatory diseases are the uncontrolled and underlying pathological mechanism of a microbial infection, inflammation is a part of body immune response, it helps in the wound healing. It’s a part of innate immunity and not adaptive immunity. Acute and chronic inflammation are differentiated accordingly on symptoms bases chronic inflammation is the long term inflammation and acute starts rapidly and creates pain, swelling, heat, immobility.

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Dermatopathology

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#Dermatopathology is the medical subspecialty of #pathology that includes surgical pathology, skin infections, skin pathology etc. The study focuses on connective tissue diseases at a microscopic and molecular level. It additionally encompasses analyses of the potential causes of skin diseases at a basic level. Dermatopathological cases may include various skin disorders including melanoma and many other immunologic, infectious and pediatric diseases of skin.

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Cytopathology

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#Cytopathology is a branch of #pathology which deals with the study of individual or free cells or tissue fragments in the disease which is extracted from tissues. Diagnostic techniques are used, which examines cells from various sites of the body which finally determines the exact cause or the nature of disease. In other words Cytopathology is the study of individual cells in disease. In contrast whole tissues are examined in the histopathology. Cytopathology is generally used to investigate diseases involving a wide range of body sites, often to aid in the diagnosis of cancer, but also in the diagnosis of some infectious diseases and other inflammatory conditions. For cytopathologic analysis, there are two methods for collecting cells: Exfoliative cytology method and Intervention cytology method.

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Stem cells Edited to fight arthritis

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The main goal is creating vaccine that targets the inflammation in joints. Using new gene-editing technology, researchers have rewired mouse stem cells to fight inflammation caused by arthritis and other chronic conditions. Such stem cells, known as SMART cells (Stem cells Modified for Autonomous Regenerative Therapy), develop into cartilage cells that produce a biologic anti-inflammatory drug that, ideally, will replace arthritic cartilage and simultaneously protect joints and other tissues from damage that occurs with chronic inflammation.

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Chemoradiotherapy

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The Combination of chemotherapy and radiotherapy is called as Chemoradiation. It is also called as chemo radiotherapy. Chemotherapy is given before surgery to help in shrink the cancer and reduce the risk of cancer coming back. This is giving the chemo and radiation at the same time when needed. Usually the radiation is completed first and then chemotherapy is done. Generally chemo radiotherapy is given to patients with rectal cancer….
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