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Primary Glaucoma and Long- Term Topical Application of 0.005% Latanoprost Effects on Intraocular Pressure in Uncontrollable used Multidrug Medications or Single used in Dogs

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Objective: To evaluate the effect of long-term topical application of 0.005% latanoprost on intraocular pressure (IOP) in dogs with primary glaucoma Animal studied: One hundred-and-five dogs with primary glaucoma. Procedure: Latanaprost was used and/or added to existing medications for a minimum of 2 months. The iridocorneal angle (ICA) was measured and graded as open, slightly narrow, narrow, or closed. Baseline IOP was established at the time of the decision to initiate latanoprost treatment. Dogs were classified as responders if the IOP decreased with treatment or as non-responders if there was no decrease in the IOP. Results: The IOP did not decrease in 14 dogs (13.3%), and decreased initially, but increased again over time in 45 dogs (42.9%).

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Serum Albumin Levels in Breast Cancer: Correlation with Overall Survival

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Albumin in an important biomarker that indicates #malnutrition as well as inflammation. The aim of the study was to evaluate the albumin levels in breast cancer patients and its association with overall survival among breast cancer patients of Malwa region of Punjab. The study was planned in Malwa region of Punjab. Sampling was done from Guru Gobind Singh Medical College and Hospital and Max Hospital. The estimation of albumin levels was done at Central University of Punjab. 250 patients with breast cancer and 250 age and sex matched controls were involved in the study. Albumin levels were estimated using fully automated bio analyzer Erba 200. Follow-up interviews were conducted at an interval of 3, 6, 12 and 15 months to determine the outcome among breast cancer patients.   In result low levels of albumin was found among the diseased in comparison with controls (p<0.000).

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The Role of Prebiotics and Probiotics in Human Health

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Human health by far depends on gut health. It is no wonder that many ancient traditional medicine practitioners and philosophers asked about bowel function when a patient presented with common ailments such as a headache and lack of energy. As far back as 400 B.C., Hippocrates was quoted as saying “…death sits in the bowels…” and “…bad digestion is the root of all evil…” in 400 B.C.

For more information: https://www.scitechnol.com/food-nutritional-disorders.php

Effects of Exogenous Spermidine on Cell Wall Composition and Carbohydrate Metabolism of Marsilea Plants under Cadmium Stress

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In an experiment to detect the cellular changes of carbohydrate content and its related enzymatic activities, a study was undertaken with Marsilea minuta L., an aquatic fern species in simulated condition of cadmium (Cd) toxicity. From the varying doses of Cd (0, 50, 100 and 200 μM) and supplemented with spermidine (2 mM), it revealed that plants were suffered from accumulation of total carbohydrate in a dose-dependent manner under Cd stress. Maximum depletion of carbohydrate content was 58% with respect to control which was retrieved by 1.42 fold with spermidine application. In a similar manner, plants were also affected with starch, total reducing sugar content by 42% and 63.04% respectively over the control. The fall in both starch and total reducing sugar were retrieved by plants by 1.32 fold and 1.52 fold, respectively.

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Arsenic Induced Changes in Growth and Physiology of Maize (Zea mays L.) Seedlings and its Possible Amelioration Using Phosphate

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The response of maize (Zea mays L.) to different levels of arsenate with or without phosphate was investigated. Arsenic exposure significantly hampered the growth of maize seedlings showing reductions in root and shoot lengths together with reductions in fresh and dry weight. The level of total chlorophyll, chlorophyll a, chlorophyll b and carotenoids decreased in arsenic treated seedlings. Arsenic toxicity was associated with an increase in the activities of the anti-oxidative scavenging enzymes catalase and peroxidase. Arsenic restricted the concentration of nucleic acids (DNA and RNA) and soluble protein content in maize seedlings.

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Bridging Stem Cell Research from Humans to Animals

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Translational stem cell research is a relatively young subspecialty of clinical research in animals. Although the success of therapeutic stem cell therapies in humans was based on research in small animal models, namely mice, development of clinical applications for farm and companion animals has been very limited so far. Because basic mechanisms regulating the physiology and function of stem cells are likely to be highly conserved between humans and animals, current  practices and techniques that have been developed for human subjects can now be translated to improve animal welfare.

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Phytoaccumulation of Chromium and Copper by Mentha spicata L.

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This paper reports a study of heavy metal absorption by Mentha spicata. M. spicata was grown in garden soil. The soil was treated with different concentrations (20 mg/l, 40 mg/l, 60 mg/l and 80 mg/l)of chromium and copper solutions. The effect of the application of the above two heavy metals was studied after 10 days of the treatment.Chromium and copper exerted toxic effects on the growth and physical parameters of Mentha spicata. M. spicata functioned as a hyper accumulator of chromium and copper. The results indicated that the reduction of growth parameters was inversely related to concentration of the heavy metals.

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