Sacroiliac Joint Dysfunction

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Sacroiliac joint pain refers to the pain arising from the SIJ joint structures. SIJ dysfunction is a potential cause of low back pain and prevalence rate of SIJ dysfunction is reportedly 13.8% to 47.9% in the general population. At the beginning of the twentieth century, the sacroiliac joint was considered the most important source of low back pain. In pregnant patients with hypermobility and laxity of the SIJ, excessive stretching and mobilization may aggravate SIJ pain. Physical therapy treatments for SIJ dysfunction usually emphasize the abdomino-lumbo-sacro-pelvic-hip complex. Treatments include: stretching, strengthening, stabilizing pelvic floor muscles, correcting gait abnormalities and addressing postural and dynamic muscle imbalance.


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Case Study of Viral Hepatitis Based on Immigration Situation

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Recently wars left the world in shell-shocked with a number of immigrants, huge numbers of people with lack of sanitary condition and hygienic practice give us a danger alarm about children future in whole countries that accepted the immigrates and under immigration system. On the other hand, the tremendous number of refugee’s increases paralleled with a number of wars happened in the last decades. The main target of this work is to focus on viral hepatitis epidemic during immigration time and shed light on this case to solve and find the best solution for it.


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Relationship among Heterosis, Combining Ability and SSR Based Genetic Distance in Single Cross Hybrids of Maize (Zea Mays L)

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Combining ability and heterosis for different morphological and quality traits were studied under three environments using 10 inbred lines, 45 single cross hybrids and three commercial hybrids as checks at SHIATS, Allahabad, India during monsoon, 2014. Ten simple sequence markers (SSR) were used to quantify genetic distance  which was further used to analyse relationship with combining ability and heterosis in single cross hybrids. Pearson’s correlation and linear regression were analysed to identify the important factors determining heterosis and per se performance of hybrids. Variances due to general combining ability (GCA) and specific combining ability (SCA) were found to be significant for all but their interaction with environments were significant only ..Read more  morphological traits. SSR marker bnlg 1523 was found as a potential marker for discriminating maize inbred lines at molecular level as it has high PIC (0.71) and gene diversity (0.74). Significant positive association were recorded Read more


Breeding Sites of Stomoxys spp (Diptera: Muscidae), a Preliminary Study in the Makokou Region (North-East-Gabon)

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In order to circumscribe the breeding sites of stomoxes in the Makokou region, eight potentially favorable environments were sampled from January to June 2007 in three habitats: primary and secondary forest (natural environments) and the anthropic environment (artificial or disturbed areas). In the primary forest, three types of substrates were collected: litter, elephant dung, and Cephalophus droppings. In the secondary forest, two types of substrates: litter and monkey droppings. In villages or cities, three substrates constituting of decaying plant material, organic waste from garbage in villages and cow dung were also collected. These materials were placed in emergence cages while awaiting the emergence of adult arthropods. In total, 14517 arthropods emerged, including 11726 stomoxes and 2791 other arthropod specimens. Seven Stomoxys spp were observed and included: S. transvittatus with 8221 (70%) emerged individuals, S. niger with 1679 (14%) observed individuals. However, S. omega (8%); S. inornatus (4%); S. calcitrans (2%); S. niger bilineatus (1.9%); and finally S. xanthomelas (0.1%) emerged in minor proportions. The results obtained in this study indicate that stomoxes can lay their eggs on several types of substrates hence colonizing many areas

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Assessment of Natural Killer Cell Subsets in HCV Infection and Hepatocellular Carcinoma

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In this study, the NK cell CD markers testings were found to be the possibility and potentiality of some types of NK cells to target HCV and HCC immunotherapy

Natural Killer (NK) cells are important for responding to and destroying cells that have become infected with virus and cancer cells. We evaluated the effects of hepatitis C virus (HCV) only infected patients and HCV-related hepatocellular carcinoma (HCC) of Egyptian cases on peripheral blood NK cell subsets CD56bright and CD56Dim NK cells, CD56dim16+, CD56dim16 and with emphasis on the CD3 cells.

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On the Existence of Animal Viroids

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This manuscript is an outgrowth of my discovery of the viroids in 1971, which has been endorsed by the International Committee for the Taxonomy of Viruses (ICTV) as a new order called Subviral Agents, which now consists of two families and upward of 40 species, all isolated from higher plants. Most of these cause diseases of various crops. fruit trees, or ornamental plants. Here I ask the question why, so far, these plant viroids are not complemented by their counterparts in animals.

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The blog of SciTechnol journals with four sections- Agri Food Aqua Vet, Environmental Science Journals, Genetics & Molecular Biology Journals, Immunology & Microbiology

Gene Therapy: Ethical Issue ..!!

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The new biotechnology is usually the useful thing for biomedical society. There are many new emerging biotechnologies that exist and widely available at present. The usefulness of the new technology can be expected. On the other hand, the possible adverse effect of the new technology should also be kept in mind. In regulation of the new biotechnology, there must be the good control of users and technologies. At present, gene therapy is a new biotechnology based on advance genetic knowledge. The advantage is medicine is expected and there is the need for control of this new technology. For control of the new technology, the new law is usually needed. Nevertheless, the better control should be the ethical control. If one has a good ethical practice, the problem should not occur. The ethical issue on gene therapy is very interesting. As noted by Fogleman et al., Read more

Epitope Mapping of a Long Peptide Candidate for Diagnosis of #Hepatitis C

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Hepatitis C is a worldwide public health problem by its high prevalence and relevance and the impact in the high incidence of liver cirrhosis and liver cancer. Previous studies identified the peptide IMT-286 (40 mer), located in the core of the virus as a possible candidate to be used in the diagnosis of Hepatitis C by ELISA. The synthesis of long peptides in addition to its higher cost may be limited by undesirable reactions (cycling, deletions, etc.) that impede the synthesis…Read more–evaluation-of-theantigenicity-by-the-multipleantigen-blot–Y5s2.php?article_id=5439

#Immunochromatographic Assay for Detection of Mycobacterium #Tuberculosis Complex in Clinical Isolates at Instituto de Infectologia Emilio Ribas, Brazil

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#Tuberculosis results in an estimated 1.5 million deaths each year and the worldwide number of new cases continues high. For decades, tuberculosis diagnosis in high-burden countries was almost completely based on sputum #microscopy. Increasing rates of drug-resistance remains a severe threat that has drawn greater attention from worldwide tuberculosis control programs. We evaluated the performance of TB Ag MPT64 Test directly from 554 BACTEC MGIT 960 (or BACTEC FX, for blood and bone marrow) culture-positive samples: 391 were identified as M. tuberculosis complex and 95 as nontuberculosis mycobacteria ..Read more

Mapping of transcription factor in human aging

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Natural maturing is an unpredictable procedure reliant on the interchange of cell self-governing and tissue logical changes which happen in light of combined sub-atomic pressure and show through versatile transcriptional reconstructing. Scientists depict a translation factor (TF) meta-examination of quality articulation datasets accumulated from 18 tissue locales gathered at various organic ages and from 7 diverse in-vitro maturing models. In-vitro maturing stages included replicative senescence and a vitality confinement demonstrate in calmness (ERiQ), in which ATP was momentarily lessened. TF themes in promoter districts of trimmed arrangements of target qualities were checked utilizing JASPAR and TRANSFAC. TF marks set up a worldwide mapping of agglomerating themes with particular groups when positioned progressively. Astoundingly, the ERiQ profile was imparted to the larger part of in-vivo matured tissues. Fitting themes in a moderate protein-protein organize permitted to test for availability to particular pressure sensors. The DNA harm sensors ATM and ATR connected to the subnetwork related with senescence. By differentiate, the vitality sensors PTEN and AMPK associated with the hubs in the ERiQ subnetwork. This study suggest that metabolic dysfunction may be linked to transcriptional patterns characteristic of many aged tissues and distinct from cumulative DNA damage associated with senescence.

Functional fine-tuning between bacterial DNA recombination

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Homologous recombination (HR) is significant for the blunder free repair of DNA double- strand breaks (DSBs) and the restart of slowed down replication. Be that as it may, uncertain HR can prompt genome unsteadiness, featuring the significance of HR quality control. After DSB arrangement, HR continues through DNA end resection and recombinase stacking, while helicase-catalyzed interruption of a subset of hence framed DNA attacks is believed to be basic for keeping up HR precision by means of repressing ill-conceived (non-allelic) recombination. Researchers demonstrated that in vitro described robotic distortions of E. coli RecBCD (resection and recombinase stacking) RecQ (multifunctional DNA-rebuilding helicase) mutant chemical variations, on one hand, in total break down cell survival under specific states of genomic push. Then again, they found that RecBCD and RecQ deserts practically remunerate each other as far as HR exactness. The anomalous long resection and ineffective recombinase stacking exercises of a mutant RecBCD complex (harboring the D1080A substitution in RecB) cause upgraded ill-conceived recombination.

The Causes of Chronic Kidney Disease in Adults in a Developing Country

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The decrease in the clearance capacity of the kidney is associated with devastating effect on almost every organ of the body. The detrimental outcome caused by chronic kidney disease (CKD), include End Stage Renal Disease (ESRD), progressive cardiovascular disease (CVD), early mortality and profound morbidity that has considerable economical impact, especially in developing countries. Globally, diabetes mellitus (DM) and hypertension (HTN) are recognized as the principal causes of CKD, while infectious diseases, indigenous medicines, environmental and industrial pollution are also important in low income countries. Due to the diversity of population in low income countries, it is a distinct challenge to determine the cause of CKD in this region. The population in this area is heterogeneous in terms of socioeconomic growth, ethnic configuration, rural urban division, disparity and access to health facilities as compared with the developed countries. This is the reason it is hard to identify the population at particular risk and therefore, it becomes a burden to extrapolate any preventative measures on this population. Hence, there is a large group of CKD patients in which cause of CKD remains “unknown”. Similarly, preventable causes of end stage renal disease (ESRD) like renal stones still prevail in the etiology of ESRD in these parts of the world.

Impact of renin-angiotensin system blockade on renal diseases

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Renin-angiotensin-System (RAS) barricade is thought to moderate renal movement in patients with incessant kidney ailment (CKD). In any case, it stays unverifiable if the routine utilization of RAS inhibitors influences renal movement and results in pre-dialysis patients with cutting edge CKD. In this multicenter review companion think about, scientists recognized 2,076 pre-dialysis patients with cutting edge CKD (organize 4 or 5) from a sum of 33,722 CKD patients. RAS bar clients were combined with non-clients for investigations utilizing opposite likelihood of treatment-weighted (IPTW) and inclination score (PS) coordinating. The results were renal demise, all-cause mortality, hospitalization for hyperkalemia, and intelligent factors as composite results. RAS bar clients demonstrated an expanded danger of renal passing in PS-coordinated investigation (risk proportion [HR], 1.381; 95% CI, 1.071– 1.781; P = 0.013), which was in concurrence with the aftereffects of IPTW examination (HR, 1.298; 95% CI, 1.123– 1.500; P < 0.001). The danger of composite results was higher in RAS bar clients in IPTW (HR, 1.154; 95% CI, 1.016– 1.310; P = 0.027), however was minor hugeness in PS coordinated examination (HR, 1.243; 95% CI, 0.996– 1.550; P = 0.054).