Case Study of Viral Hepatitis Based on Immigration Situation

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Recently wars left the world in shell-shocked with a number of immigrants, huge numbers of people with lack of sanitary condition and hygienic practice give us a danger alarm about children future in whole countries that accepted the immigrates and under immigration system. On the other hand, the tremendous number of refugee’s increases paralleled with a number of wars happened in the last decades. The main target of this work is to focus on viral hepatitis epidemic during immigration time and shed light on this case to solve and find the best solution for it.

 

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Relationship among Heterosis, Combining Ability and SSR Based Genetic Distance in Single Cross Hybrids of Maize (Zea Mays L)

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Combining ability and heterosis for different morphological and quality traits were studied under three environments using 10 inbred lines, 45 single cross hybrids and three commercial hybrids as checks at SHIATS, Allahabad, India during monsoon, 2014. Ten simple sequence markers (SSR) were used to quantify genetic distance  which was further used to analyse relationship with combining ability and heterosis in single cross hybrids. Pearson’s correlation and linear regression were analysed to identify the important factors determining heterosis and per se performance of hybrids. Variances due to general combining ability (GCA) and specific combining ability (SCA) were found to be significant for all but their interaction with environments were significant only ..Read more  morphological traits. SSR marker bnlg 1523 was found as a potential marker for discriminating maize inbred lines at molecular level as it has high PIC (0.71) and gene diversity (0.74). Significant positive association were recorded Read more

https://www.scitechnol.com/abstract/relationship-among-heterosis-combining-ability-and-ssr-based-genetic-distance-in-single-cross-hybrids-of-maize-zea-mays-l-6022.html

 

Breeding Sites of Stomoxys spp (Diptera: Muscidae), a Preliminary Study in the Makokou Region (North-East-Gabon)

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In order to circumscribe the breeding sites of stomoxes in the Makokou region, eight potentially favorable environments were sampled from January to June 2007 in three habitats: primary and secondary forest (natural environments) and the anthropic environment (artificial or disturbed areas). In the primary forest, three types of substrates were collected: litter, elephant dung, and Cephalophus droppings. In the secondary forest, two types of substrates: litter and monkey droppings. In villages or cities, three substrates constituting of decaying plant material, organic waste from garbage in villages and cow dung were also collected. These materials were placed in emergence cages while awaiting the emergence of adult arthropods. In total, 14517 arthropods emerged, including 11726 stomoxes and 2791 other arthropod specimens. Seven Stomoxys spp were observed and included: S. transvittatus with 8221 (70%) emerged individuals, S. niger with 1679 (14%) observed individuals. However, S. omega (8%); S. inornatus (4%); S. calcitrans (2%); S. niger bilineatus (1.9%); and finally S. xanthomelas (0.1%) emerged in minor proportions. The results obtained in this study indicate that stomoxes can lay their eggs on several types of substrates hence colonizing many areas

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Assessment of Natural Killer Cell Subsets in HCV Infection and Hepatocellular Carcinoma

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In this study, the NK cell CD markers testings were found to be the possibility and potentiality of some types of NK cells to target HCV and HCC immunotherapy

Natural Killer (NK) cells are important for responding to and destroying cells that have become infected with virus and cancer cells. We evaluated the effects of hepatitis C virus (HCV) only infected patients and HCV-related hepatocellular carcinoma (HCC) of Egyptian cases on peripheral blood NK cell subsets CD56bright and CD56Dim NK cells, CD56dim16+, CD56dim16 and with emphasis on the CD3 cells.

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On the Existence of Animal Viroids

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This manuscript is an outgrowth of my discovery of the viroids in 1971, which has been endorsed by the International Committee for the Taxonomy of Viruses (ICTV) as a new order called Subviral Agents, which now consists of two families and upward of 40 species, all isolated from higher plants. Most of these cause diseases of various crops. fruit trees, or ornamental plants. Here I ask the question why, so far, these plant viroids are not complemented by their counterparts in animals.

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The blog of SciTechnol journals with four sections- Agri Food Aqua Vet, Environmental Science Journals, Genetics & Molecular Biology Journals, Immunology & Microbiology

Side alternating vibration

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Vibration exercise generates sinusoidal oscillations, and the load depends on frequency, amplitude, acceleration, and duration. During side-alternating vibration, the transfer of vibration is not synchronous; instead, it operates in a side-alternating way so the right foot is lowest when the left foot is highest. Researchers have suggested that SAV produces a reciprocal vertical displacement on the left and right sides of a fulcrum and continuous rotational movements around the hip and lumbosacral joints. Whole-body vibration improves balance and mobility, the control of posture is accomplished by stereotyped muscle-activation  patterns because these are reflected in the hip and ankle strategies. The ankle invertors and evertors play a negligible role due to their limited moment-of-force capability. Vibration training could have delayed effects due to the high intensity of the training and induces acute micro damage and the system requires a longer time to recover.

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Pregnancy-Associated Plasma Protein A

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Pregnancy-associated plasma protein-A (PAPP-A) largest of the pregnancy associated proteins produced by both the embryo and the placenta during pregnancy .This protein is thought to have several different functions, including preventing recognition of the fetus by the maternal immune system, matrix mineralization and angiogenesis.it was first found in the serum of pregnant women and has been used as a marker of Down’s syndrome in the first trimester .Researcher  identified a marked increase in PAPP‐A levels in patients with both myocardial infarction and unstable angina, the levels did not correlate with the number of coronary stenoses identified at angiography.

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Osteoporosis

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Osteoporosis is a condition characterized by a decrease in the density of bone, decreasing its strength and resulting in fragile bones. Osteoporosis literally leads to abnormally porous bone that is compressible, like a sponge. Normal bone is composed of protein, collagen, and calcium, all of which give bone its strength. It’s a silent killer affecting the quality of life due to fractures and postural changes. Bones that are affected by osteoporosis can break (fracture) with relatively minor injury that normally would not cause a bone to fracture. Elderly people with osteoporosis can decrease their risk for hip fracture by maintaining muscle strength, coordination, and balance with exercise programs. Estrogen therapy and progesterone therapy (ET/EPT) is no longer recommended as a first-line therapy for the prevention of osteoporosis. They may be used in the therapy for osteoporosis in women under 60.The drugs used in osteoporosis may be those that inhibit bone resorption bisphosphonates, denosumab, calcitonin, SERMs, estrogen and progesterone or that stimulate bone formation PTH, Teriparatide.

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Novel players [Non-coding RNAs] in β cell and type 1 diabetes

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Type 1 diabetes (T1D) is a chronic immune-mediated disease resulting from selective destruction of insulin-producing pancreatic islet β cells. A complex interplay between several environmental and genetic risk factors contributes to the onset of T1D. Long non-coding RNA are a sub-class within non-coding RNA.Recent study show  more than 50 genomic risk loci have been identified for T1D.50% of the genetic risk for T1D is known to reside within the human leukocyte antigen region, other non-HLA disease susceptibility loci have been identified based on their direct influence on the risk non-coding variants affecting regulatory elements have the potential to perturb chromatin folding leading to mis-expression of the target gene. These recent facts suggest that the regulatory landscape of human genome plays an important role in pathology of a disease and newer approaches are needed to identify putative regulatory risk variants affecting gene regulation and immune function.

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Mutational analysis of genes in osteogenesis imperfect patient

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Osteogenesis imperfect (OI) is a group of genetic disorders that mainly affect the bones. The term “ontogenesis imperfecta” means imperfect bone formation. Osteogenesis imperfecta is a rare bone disorder. In 90% of cases, OI is caused by mutations in the COL1A1/2 genes, which code procollagen α1 and α2 chains. The milder forms of osteogenesis imperfecta, including type I, are characterized by bone fractures during childhood and adolescence that often result from minor trauma. Fractures occur less frequently in adulthood. The genetics of the disorder reflect the complexity of the OI phenotype range. Up to 21 different genes have been associated with occurrence of OI.Studies have shown that the primary cause of OI are mutations in the COL1A1/2 genes, which code procollagen type I α1 and α2 chains.

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Skeleton

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Skeleton acts as a supporting structure of an organism. The organisms with skeleton are known as vertebrates and without skeleton are known as invertebrates. There are different types of skeleton; they are exoskeleton, endoskeleton, cytoskeleton, hydro skeleton, pliant skeleton and rigid skeleton. Mostly at the age of 21, the bone masses of the skeleton reaches its maximum density. The primary function of skeleton is to support, movement, protection, production of blood cells, storage of minerals, and endocrine regulation.

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Effects of Exogenous Spermidine on Cell Wall Composition and Carbohydrate Metabolism of Marsilea Plants under Cadmium Stress

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In an experiment to detect the cellular changes of carbohydrate content and its related enzymatic activities, a study was undertaken with Marsilea minuta L., an aquatic fern species in simulated condition of cadmium (Cd) toxicity. From the varying doses of Cd (0, 50, 100 and 200 μM) and supplemented with spermidine (2 mM), it revealed that plants were suffered from accumulation of total carbohydrate in a dose-dependent manner under Cd stress. Maximum depletion of carbohydrate content was 58% with respect to control which was retrieved by 1.42 fold with spermidine application. In a similar manner, plants were also affected with starch, total reducing sugar content by 42% and 63.04% respectively over the control. The fall in both starch and total reducing sugar were retrieved by plants by 1.32 fold and 1.52 fold, respectively.

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